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1.
J Bodyw Mov Ther ; 31: 7-15, 2022 07.
Artículo en Inglés | MEDLINE | ID: mdl-35710224

RESUMEN

BACKGROUND: Chronic low back pain due to manual lifting continues to be one of the significant common public health challenges in modern societies despite increased automation. While there are extensive studies on the biomechanics of lifting as associated with LBP, the role of unstable and time-varying dynamic loads, quite common in industrial lifting and daily life, remains elusive. OBJECTIVES: The present study aimed to investigate the response of trunk muscles in subjects with chronic non-specific low back pain (CNLBP) while holding unstable dynamic loads. METHODS: Twelve male patients with CNLBP and twelve healthy controls participated in this cross-sectional study. The subjects held static and dynamic loads in neutral positions. Normalized EMG data of the trunk muscles were captured and analyzed by repeated-measures ANOVA test. RESULTS: The low back pain group demonstrated significantly higher activation levels of the internal and external abdominal oblique muscles while holding dynamic loads (p < 0.05). CONCLUSION: Our results suggest that the neuromusculoskeletal system in low back patients holding dynamic loads may invoke a motor control strategy that significantly increases muscle co-activation leading to higher joint stiffness at the expense of higher compressive loads on the lumbar spine. Importantly, the type of load plays a critical role in terms of external perturbations that may lead to spinal injury in CNLBP patients and must, therefore, be considered in the risk prevention and assessment of lifting and other manual material handling tasks.


Asunto(s)
Dolor de la Región Lumbar , Fenómenos Biomecánicos , Estudios Transversales , Electromiografía/métodos , Humanos , Vértebras Lumbares , Masculino , Músculo Esquelético/fisiología , Soporte de Peso/fisiología
2.
Res Sports Med ; 29(6): 586-592, 2021.
Artículo en Inglés | MEDLINE | ID: mdl-34477036

RESUMEN

This study examined the biomechanics of the lower limbs during four typical Tai Chi (TC) movements: wave hand in cloud, leaning fly side, repulse monkey, and brush knee and twist step, in order to provide biomechanical evidence-based recommendations for patients with knee osteoarthritis (OA) practicing TC. Joint angles and joint moments of the hip, knee, and ankle in frontal and sagittal plane as well as ground reaction forces were examined while performing TC and regular walking in an experienced 38 years old TC master. The results showed that relative to walking, the four TC movements are characterized by a wide motion range of lower limbs, slow increase in joint loading, and strong muscle activity during performance. Therefore, these TC movements could be suitable for patients with knee OA to practice for improving the muscle strength of their lower limbs and functional ability.


Asunto(s)
Extremidad Inferior/fisiología , Osteoartritis de la Rodilla/fisiopatología , Osteoartritis de la Rodilla/rehabilitación , Rango del Movimiento Articular/fisiología , Taichi Chuan/métodos , Caminata/fisiología , Soporte de Peso/fisiología , Adulto , Fenómenos Biomecánicos , Humanos , Cinética , Masculino
4.
Nutrients ; 13(3)2021 Mar 03.
Artículo en Inglés | MEDLINE | ID: mdl-33802283

RESUMEN

This study assessed the effects of a 7-day creatine (CRE) supplementation on the load-velocity profile and repeated sub-maximal bouts in the deep squat using mean propulsive velocity (MPV) and mean propulsive power (MPP). Eleven strength-trained men (31.4 ± 5.4 years) supplemented 0.3 g·kg-1·d-1 CRE or a placebo (PLA, maltodextrin) for seven days in a randomized order, separated by a 30-day washout period. Prior to and after the supplementation, the subjects performed an incremental maximal strength (1RM) test, as well as 3 × 10 repetitions and a repetitions-to-failure test (RFT), all at 70% 1RM. Maximal strength remained statistically unaltered in CRE (p = 0.107) and PLA (p = 0.568). No statistical main effect for time (p = 0.780) or interaction (p = 0.737) was observed for the load-velocity profile. The number of repetitions during RFT remained statistically unaltered in both conditions (CRE: +16.8 ± 32.8%, p = 0.112; PLA: +8.2 ± 47.2%, p = 0.370), but the effect size was larger in creatine compared to placebo (g = 0.51 vs. g = 0.01). The total work during RFT increased following creatine supplementation (+23.1 ± 35.9%, p = 0.043, g = 0.70) but remained statistically unaltered in the placebo condition (+15.0 ± 60.8%, p = 0.801, g = 0.08; between conditions: p = 0.410, g = 0.25). We showed that CRE loading over seven days did not affect load-velocity characteristics but may have increased total work and power output during submaximal deep squat protocols, as was indicated by moderate effect sizes.


Asunto(s)
Creatina/administración & dosificación , Suplementos Dietéticos , Tolerancia al Ejercicio/efectos de los fármacos , Músculo Esquelético/efectos de los fármacos , Soporte de Peso/fisiología , Adulto , Estudios Cruzados , Método Doble Ciego , Humanos , Masculino , Fuerza Muscular/efectos de los fármacos , Entrenamiento de Fuerza/métodos
5.
Sci Rep ; 11(1): 6414, 2021 03 19.
Artículo en Inglés | MEDLINE | ID: mdl-33742012

RESUMEN

High-intensity interval training (HIIT) is of scientific interest due its role in improving physical fitness, but the effects of HIIT on bone health need be carefully explored. Further, it is necessary to know whether HIIT effects on bone health are dependent on the physical activity levels. This may be experimentally tested since we have built a large cage (LC) that allows animals to move freely, promoting an increase of spontaneous physical activity (SPA) in comparison to a small cage (SC). Thus, we examined the effects of HIIT on biophysical, biomechanical and biochemical parameters of bone tissue of C57BL/6J mice living in cages of two different sizes: small (SC) or large (LC) cages with 1320 cm2 and 4800 cm2 floor space, respectively. Male mice were subdivided into two groups within each housing type: Control (C) and Trained (T). At the end of the interventions, all mice were euthanized to extract the femur bone for biophysical, biomechanical and biochemical analyses. Based a significant interaction from two-way ANOVA, trained mice kept in large cage (but not for trained mice housed in SC) exhibited a reduction of tenacity and displacement at failure in bone. This suggests that long-term HIIT program, in addition with a more active lifestyle correlates with exerts negative effects on the bone of healthy mice. A caution must also be raised about the excessive adoption of physical training, at least regarding bone tissue. On the other hand, increased calcium was found in femur of mice housed in LC. In line with this, LC-C mice were more active (i.e. SPA) than other groups. This implies that an active lifestyle without long-term high intensity physical training seems to play a role in promoting benefits to bone tissue. Our data provides new insights for treatment of osteo-health related disorders.


Asunto(s)
Fémur/química , Fémur/fisiología , Entrenamiento de Intervalos de Alta Intensidad/efectos adversos , Condicionamiento Físico Animal/fisiología , Aptitud Física/fisiología , Animales , Densidad Ósea/fisiología , Calcio/análisis , Vivienda para Animales , Masculino , Ratones , Ratones Endogámicos C57BL , Fósforo/análisis , Conducta Sedentaria , Soporte de Peso/fisiología
6.
J Manipulative Physiol Ther ; 44(1): 56-60, 2021 01.
Artículo en Inglés | MEDLINE | ID: mdl-33257083

RESUMEN

OBJECTIVE: The aim of this study was to evaluate the interexaminer and intraexaminer reliability of classification with the Viladot method of plantar impression obtained by means of a footprinting mat. METHODS: Footprints were taken from 40 participants using a footprinting mat. The images were subjected to analysis by 3 independent examiners. To investigate intraexaminer reliability, the analysis was repeated by 1 of the examiners 1 week later. RESULTS: Excellent intraexaminer reliability was found (κ = 1.0; 95% confidence interval [CI], 0.77-1.0; P < .00). For interexaminer reliability, in the right foot high concordance was found for typical feet (κp = 0.76; 95% CI, 0.58-0.93; P < .00) and excellent concordance for cavus feet and flat feet (respectively: κp = 0.86; 95% CI, 0.68-1.0; P < .00; and κp = 0.81; 95% CI, = 0.63-0.99; P < .00). In the left foot high concordance was observed between the 3 evaluators for typical feet and cavus feet (respectively: κp = 0.75; 95% CI, 0.57-0.93; P < .00; and κp = 0.69; 95% CI, 0.51-0.87; P < .00) and excellent concordance for flat feet (κp = 1.0; 95% CI, 0.82-1.0; P < .00). CONCLUSION: The Viladot method is reliable for analyses involving 1 or more examiners, presenting excellent intraexaminer reliability and high to excellent interexaminer reliability. The Viladot method is a reliable (replicable and consistent) instrument, that is, its repeated application to the same subject produces similar results.


Asunto(s)
Pie/fisiología , Examen Físico/normas , Soporte de Peso/fisiología , Niño , Humanos , Masculino , Variaciones Dependientes del Observador , Pronación/fisiología , Reproducibilidad de los Resultados , Proyectos de Investigación , Supinación/fisiología
7.
J Rehabil Med ; 52(8): jrm00092, 2020 Aug 31.
Artículo en Inglés | MEDLINE | ID: mdl-32778903

RESUMEN

BACKGROUND: Ambulant biofeedback devices can be used to provide real-time feedback for trauma patients on weight-bearing regimes. The devices also enable prescribing clinicians to monitor and train patients' level of weight-bearing. However, there is limited evidence regarding the feasibility of use of such devices in controlling weight-bearing, and their full potential remains to be elucidated. OBJECTIVE: To investigate the feasibility of using ambulant biofeedback training devices to improve compliance with weight-bearing regimes in trauma patients with lower extremity fractures. METHODS: A literature review of the feasibility and clinical validity of ambulant biofeedback devices. RESULTS: Three clinically validated biofeedback devices were found feasible for use in monitoring the compliance of patients who have lower extremity fractures with different weight-bearing regimes. CONCLUSION: Further information about the feasibility and clinical validity of biofeedback training devices is nee-ded in order to optimize weight-bearing instructions for patients.


Asunto(s)
Biorretroalimentación Psicológica/métodos , Fracturas Óseas/terapia , Extremidad Inferior/lesiones , Soporte de Peso/fisiología , Heridas y Lesiones/terapia , Estudios de Factibilidad , Femenino , Humanos , Masculino , Cooperación del Paciente , Reproducibilidad de los Resultados
8.
J Musculoskelet Neuronal Interact ; 20(1): 4-11, 2020 03 03.
Artículo en Inglés | MEDLINE | ID: mdl-32131365

RESUMEN

The Maternal Vitamin D Osteoporosis (MAVIDOS) trial reported higher total body bone mineral content in winter-born infants of mothers receiving vitamin D supplementation [1000 IU/day cholecalciferol] compared with placebo from 14 weeks gestation until delivery. This sub-study aimed to determine whether antenatal vitamin D supplementation altered postnatal bone formation in response to mechanical stimulation. Thirty-one children born to MAVIDOS participants randomised to either placebo (n=19) or cholecalciferol (n=12) were recruited at age 4-5 years. Children received whole body vibration (WBV) for 10 minutes on 5 consecutive days. Fasting blood samples for bone homeostasis, 25 hydroxyvitamin D (25OHD), parathyroid hormone (PTH), and bone turnover markers (Pro-collagen Type 1 N-terminal propeptide, P1NP; Cross-linked C-telopeptide of Type I Collagen, CTX) were collected pre-WBV and on day 8 (D8). Mean changes (D) in P1NP (ng/ml) between baseline and D8 in the vitamin-D intervention and placebo groups were 40.6 and -92.6 respectively and mean changes (Δ) in CTX (ng/ml) were 0.034 (intervention) and -0.084 (placebo) respectively. Between-group DP1NP difference was 133.2ng/ml [95% CI 0.4, 266.0; p=0.049] and ΔCTX 0.05ng/ml (95% CI -0.159, 0.26ng/mL; p=0.62). Antenatal vitamin-D supplementation resulted in increased P1NP in response to WBV, suggesting early life vitamin D supplementation increases the anabolic response of bone to mechanical loading in children.


Asunto(s)
Densidad Ósea/efectos de los fármacos , Colecalciferol/administración & dosificación , Osteogénesis/efectos de los fármacos , Estimulación Física/métodos , Atención Prenatal/métodos , Fenómenos Fisiologicos de la Nutrición Prenatal/efectos de los fármacos , Soporte de Peso , Densidad Ósea/fisiología , Preescolar , Femenino , Humanos , Masculino , Osteogénesis/fisiología , Embarazo , Atención Prenatal/tendencias , Fenómenos Fisiologicos de la Nutrición Prenatal/fisiología , Estudios Prospectivos , Vibración , Vitamina D/administración & dosificación , Vitamina D/sangre , Soporte de Peso/fisiología
9.
Transfusion ; 60(5): 918-921, 2020 05.
Artículo en Inglés | MEDLINE | ID: mdl-32052859

RESUMEN

BACKGROUND: A new national donor safety initiative was introduced in Australia in 2018, which aimed to encourage all whole blood donors to water load and to use applied muscle tension. This study evaluated the effect of this initiative on the rate of vasovagal reactions (VVR). STUDY DESIGN AND METHODS: Routinely collected data were used to identify whole blood donations and any associated VVRs before (n = 167,056 donations) and after implementation (n = 215,572 donations). Multivariate logistic regression analyses were performed to evaluate the differences in VVR rates. RESULTS: The total rate of VVRs declined from 22.5 per 1000 donations to 20.6 per 1000 donations after implementation, a reduction of 8% (p < 0.001). The rate of presyncopal reactions decreased by 8% in new donors and 12% in repeat donors. No impact was observed on the rate of syncope in any of the groups. The multivariate logistic regression analysis demonstrated the odds of experiencing a presyncopal reaction was reduced by 13% following implementation, with no significant effects on syncope. CONCLUSION: The findings of this study support the use of water loading and applied muscle tension in routine whole blood collection to reduce the incidence of VVRs.


Asunto(s)
Donantes de Sangre , Implementación de Plan de Salud , Tono Muscular/fisiología , Manipulaciones Musculoesqueléticas/métodos , Seguridad del Paciente/normas , Síncope Vasovagal/prevención & control , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Australia/epidemiología , Donantes de Sangre/psicología , Donantes de Sangre/estadística & datos numéricos , Femenino , Implementación de Plan de Salud/normas , Humanos , Incidencia , Masculino , Persona de Mediana Edad , Manipulaciones Musculoesqueléticas/normas , Flebotomía/efectos adversos , Flebotomía/métodos , Flebotomía/normas , Flebotomía/estadística & datos numéricos , Factores de Riesgo , Conducta de Reducción del Riesgo , Síncope Vasovagal/epidemiología , Síncope Vasovagal/etiología , Agua , Soporte de Peso/fisiología , Adulto Joven
10.
Injury ; 51 Suppl 2: S15-S17, 2020 May.
Artículo en Inglés | MEDLINE | ID: mdl-31948779

RESUMEN

Treatment of trauma patients and fractures has changed dramatically throughout the years. From conservative methods to nowadays various kinds of screws, pins, plates and nails for optimal fixation of fractures. This lead to changes in post-operative management as well, from bedrest to (partial) weight bearing. Some patients however have very limited to no ability to mobilise, such as critical ill patients on the Intensive Care Unit, amputees or spinal cord injured patients. Due to innovations such as hydrotherapy, osseointegrated prosthesis and exoskeletons, even these people can mobilise. Thanks to innovations like these an increasing number of trauma patients are able to fully reintegrate into community life and get back to an active and independent life style.


Asunto(s)
Amputados/rehabilitación , Ambulación Precoz/métodos , Fracturas Óseas/rehabilitación , Oseointegración/fisiología , Soporte de Peso/fisiología , Humanos , Hidroterapia , Modalidades de Fisioterapia , Implantación de Prótesis
11.
Phys Ther ; 100(4): 645-652, 2020 04 17.
Artículo en Inglés | MEDLINE | ID: mdl-31944252

RESUMEN

BACKGROUND: Ankle range of motion declines with age, affecting mobility and postural control. OBJECTIVE: The objective of this study was to investigate the effects of a talus mobilization-based intervention among healthy community-dwelling older adults presenting with limited weight-bearing ankle dorsiflexion range of motion and determine how ankle mobility evolved over the treatment. DESIGN: This was a randomized clinical trial. SETTING: This study was conducted in an outpatient clinic. PARTICIPANTS: Community-dwelling, older adults over 60 years of age who had limited ankle mobility participated in this study. INTERVENTIONS: The experimental intervention consisted of 6 sessions of manual therapy applied in the ankle joint. The control group received the same volume of sham treatment. MEASUREMENTS: The primary outcome was the weight-bearing ankle dorsiflexion range of motion as measured using the lunge test. Data were collected at 9 time points: baseline, after each session, and follow-up. RESULTS: A total of 36 participants were analyzed. A single session of mobilization increased ankle range of motion by 8 degrees (95% confidence interval = 6 to 11). At the end of the sixth session, this effect had increased slightly to 11 degrees (95% confidence interval = 9 to 13). Significant between-group differences were found throughout the intervention. LIMITATIONS: Optimal dose and effects from follow-up evaluations for treatment volumes of fewer than 6 sessions remain unknown. CONCLUSIONS: Six sessions of a talus mobilization-based intervention in healthy community-dwelling older adults found that the greatest mobility gain in terms of the weight-bearing ankle dorsiflexion range of motion is produced after the first session. Additional sessions produce smaller improvements with a slight upward trend. Importantly, the restoration of joint mobility is enhanced over time after the end of the intervention.


Asunto(s)
Articulación del Tobillo/fisiología , Manipulaciones Musculoesqueléticas/métodos , Rango del Movimiento Articular/fisiología , Astrágalo/fisiología , Soporte de Peso/fisiología , Anciano , Envejecimiento/fisiología , Atención Ambulatoria , Intervalos de Confianza , Femenino , Humanos , Masculino , Persona de Mediana Edad , Manipulaciones Musculoesqueléticas/estadística & datos numéricos , Posicionamiento del Paciente , Resultado del Tratamiento
12.
Spinal Cord ; 58(1): 78-85, 2020 Jan.
Artículo en Inglés | MEDLINE | ID: mdl-31312016

RESUMEN

STUDY DESIGN: Randomized controlled trial. OBJECTIVE: To determine the effects of advanced weight-bearing mat exercises (AWMEs) with/without functional electrical stimulation (FES) of the quadriceps and gastrocnemius muscles on the ability of wheelchair-dependent people with spinal cord injury (SCI) to transfer and attain independence in activities of daily living (ADLs). SETTING: An outpatient clinic, Iran. METHODS: People with traumatic chronic paraplegia (N = 16) were randomly allocated to three groups. The exercise group (EX; N = 5) performed AWMEs of quadruped unilateral reaching and tall-kneeling for 24 weeks (3 days/week). Sessions were increased from 10 min to 54 min over the 24-week period. The exercise-FES group (EX + FES; N = 5) performed AWMEs simultaneously with FES of the quadriceps and gastrocnemius muscles. The control group performed no exercise and no FES (N = 6). The primary outcomes were the total Spinal Cord Independence Measure-III (SCIM-III) to reflect independence with ADL, and the sum of the four SCIM-III transfer items to reflect ability to transfer. There were six other outcomes. RESULTS: The mean (95% CI) between-group differences of the four transfer items of the SCIM-III for the EX vs. control group was 1.8 points (0.2-3.4), and for the EX + FES vs. control group was 2 points (0.4-3.6). The equivalent differences for the total SCIM-III scores were 2.7 points (-0.6-6.0) and 4.1 points (0.8-7.4), respectively. There were no significant between-group differences for any other outcomes. CONCLUSIONS: Advanced weight-bearing mat exercises improve the ability of wheelchair-dependent people with SCI to transfer and attain independence in ADL.


Asunto(s)
Actividades Cotidianas , Terapia por Estimulación Eléctrica/métodos , Terapia por Ejercicio/métodos , Músculo Esquelético , Evaluación de Resultado en la Atención de Salud , Paraplejía/rehabilitación , Traumatismos de la Médula Espinal/rehabilitación , Soporte de Peso , Adulto , Terapia Combinada , Femenino , Humanos , Masculino , Limitación de la Movilidad , Músculo Esquelético/fisiopatología , Paraplejía/etiología , Traumatismos de la Médula Espinal/complicaciones , Soporte de Peso/fisiología , Silla de Ruedas
13.
Ergonomics ; 62(11): 1439-1449, 2019 Nov.
Artículo en Inglés | MEDLINE | ID: mdl-31389759

RESUMEN

Inspiratory Muscle Training (IMT) whilst adopting body positions that mimic exercise (functional IMT; IMTF) improves running performance above traditional IMT methods in unloaded exercise. We investigated the effect of IMTF during load carriage tasks. Seventeen males completed 60 min walking at 6.5 km·h-1 followed by a 2.4 km load carriage time-trial (LCTT) whilst wearing a 25 kg backpack. Trials were completed at baseline; post 4 weeks IMT (consisting of 30 breaths twice daily at 50% of maximum inspiratory pressure) and again following either 4 weeks IMTF (comprising four inspiratory loaded core exercises) or maintenance IMT (IMTCON). Baseline LCTT was 15.93 ± 2.30 min and was reduced to 14.73 ± 2.40 min (mean reduction 1.19 ± 0.83 min, p < 0.01) after IMT. Following phase two, LCTT increased in IMTF only (13.59 ± 2.33 min, p < 0.05) and was unchanged in post-IMTCON. Performance was increased following IMTF, providing an additional ergogenic effect beyond IMT alone. Practitioner Summary: We confirmed the ergogenic benefit of Inspiratory Muscle Training (IMT) upon load carriage performance. Furthermore, we demonstrate that functional IMT methods provide a greater performance benefit during exercise with thoracic loads. Abbreviations: [Lac-]B: blood lactate; FEV1: forced expiratory volume in one second; FEV1/FVC: forced expiratory volume in one second/forced vital capacity ratio; FVC: forced vital capacity; HR: heart rate; IMT: inspiratory muscle training; IMTCON: inspiratory muscle training maintenance; IMTF: functional inspiratory muscle training; LC: load carriage; LCTT: load carriage time trial; Pdi: transdiaphragmatic pressure; PEF: peak expiratory flow; PEmax: maximum expiratory mouth pressure; PImax: maximum inspiratory mouth pressure; RPE: rating of perceived exertion; RPEbreating: rating of perceived exertion for the breathing; RPEleg: rating of perceived exertion for the legs; SEPT: sport-specific endurance plank test; V̇ O2: oxygen consumption; V̇ O2peak: peak oxygen consumption.


Asunto(s)
Ejercicios Respiratorios/métodos , Inhalación/fisiología , Músculos Respiratorios/fisiología , Soporte de Peso/fisiología , Adolescente , Adulto , Humanos , Elevación , Masculino , Mecánica Respiratoria , Adulto Joven
14.
South Med J ; 112(8): 428-432, 2019 08.
Artículo en Inglés | MEDLINE | ID: mdl-31375839

RESUMEN

OBJECTIVES: Individuals with intellectual disabilities (IDs) are at increased risk for low bone mass and fragility fractures, and those who are nonambulatory may be at even higher risk. Patients with IDs often are vitamin D deficient, but there is little information concerning how vitamin D treatment of patients with IDs affects markers of bone formation and resorption. METHODS: We performed a retrospective analysis of 23 institutionalized individuals with IDs who were the subject of a performance improvement continuing medical education project designed to reduce risk for fracture by optimizing serum vitamin D levels. Patients were divided into those with normal weight-bearing (NWB) physical activity (15 patients: 14 men, 1 woman) and those with low weight-bearing (LWB) physical activity (8 patients: 7 men, 1 woman). All of the subjects received 50,000 IU of vitamin D3 weekly for 4 to 8 weeks, followed by a maintenance dose of 50,000 IU monthly for 3 to 6 months. Bone turnover markers (type 1 cross-linked C-telopeptide [CTX], type 1 N-terminal propeptide [P1NP], and parathyroid hormone [PTH]) and 25(OH)-vitamin D levels were measured before and after vitamin D supplementation. RESULTS: At baseline, there were no significant differences in the serum levels of 25OH-D, PTH, P1NP, or CTX between the two groups (NWB and LWB). Vitamin D levels were increased to a higher value in LWB subjects than in NWB subjects (61 ± 4.1 vs 48.4 ± 2.2 ng/mL, P < 0.001). Vitamin D treatment suppressed PTH (20.5% ± 14.3% vs 31.4% ± 7.7%, P = not significant) and P1NP (33.0% ± 6.2% vs 29.4% ± 6.9%, P = not significant) similarly in both groups. Although CTX levels declined by 26.4% ± 5.3% (P = 0.0002) in NWB individuals (as anticipated), vitamin D supplementation resulted in an unexpected 25.8% ± 8% increase (P = 0.01) in CTX in LWB individuals, suggesting osteoclast activation. CONCLUSIONS: Although high-dose vitamin D appeared to suppress osteoclast activity in NWB adults with IDs, the increase in serum CTX levels in those with LWB activity implies activation of osteoclasts that could exacerbate their unique low bone mass and increase fracture risk. The results support the use of a lower-dose vitamin D regimen in this patient group with LWB.


Asunto(s)
Remodelación Ósea/efectos de los fármacos , Resorción Ósea/prevención & control , Ejercicio Físico/fisiología , Discapacidad Intelectual/complicaciones , Discapacidad Intelectual/tratamiento farmacológico , Vitamina D/farmacología , Soporte de Peso/fisiología , Adulto , Densidad Ósea/efectos de los fármacos , Resorción Ósea/etiología , Resorción Ósea/metabolismo , Suplementos Dietéticos , Femenino , Humanos , Masculino , Persona de Mediana Edad , Estudios Retrospectivos , Vitaminas/farmacología , Adulto Joven
15.
BMJ Open ; 9(6): e026833, 2019 06 07.
Artículo en Inglés | MEDLINE | ID: mdl-31175196

RESUMEN

OBJECTIVE: Many people of all ages suffer from vertigo due to different reasons. The comparison of patient data with standard values can highlight deteriorations or changes in postural control and thus indicate, for example, an increased risk of falling. Our aim is to measure standard values for the postural control of young healthy women. DESIGN: Observational study. SETTING: Institute of Occupational Medicine, Social Medicine and Environmental Medicine, Goethe-University Frankfurt/Main. PARTICIPANTS: 106 healthy German female subjects aged between 21 and 30 years (25±2.7 years) were measured. Their average body mass index (BMI) was 21.1±2.61 kg/m². OUTCOME MEASURES: A pressure measuring platform was used to measure the weight distribution and postural sway in habitual standing. Median, tolerance range and CI were calculated. RESULTS: Height, weight and BMI are comparable to the average young German female population. The load distribution between right and left foot was 49.91%:50.09%. The forefoot was less loaded than the rear foot (33.3%:66.67%). The right rear foot carried most of the body weight (34.34%). The average body sway was 9.50 mm in the frontal and 13.00 mm in the sagittal plane. CONCLUSIONS: Standard values for the postural control of the women aged 21-30 years correlate with the already collected data of healthy subjects and can therefore be described as representative. The standard values enable diagnosing and treating impaired balance.


Asunto(s)
Equilibrio Postural/fisiología , Postura/fisiología , Medicina Deportiva , Soporte de Peso/fisiología , Adulto , Fenómenos Biomecánicos , Índice de Masa Corporal , Femenino , Antepié Humano , Alemania , Humanos , Valores de Referencia
16.
Foot (Edinb) ; 39: 55-59, 2019 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-30974341

RESUMEN

BACKGROUND: Motion of the ankle is essential for many yoga poses. An understanding of range of ankle motion during typical yoga poses may help the clinician to understand expected outcomes of patients when returning from ankle surgery or injury to yoga. METHODS: The biomechanics of twenty healthy active yogis were collected during seven yoga poses that are common within their practices. Motion capture and force plates were used to assess the range of motion and joint moments of the ankle for each pose. RESULTS: All poses resulted in plantarflexion and external rotation moments at the ankle joints. Joint loading was highest in single leg poses. The arc of motion used by the study participants in the poses was 29° of sagittal motion, 20° of frontal motion and 35° of transverse motion. DISCUSSION: Ankle motion was evaluated when healthy yogis perform standard poses. These results may help in discussion with patients regarding expected outcomes after ankle injury or surgery.


Asunto(s)
Articulación del Tobillo/fisiología , Rango del Movimiento Articular/fisiología , Yoga , Adulto , Femenino , Humanos , Masculino , Persona de Mediana Edad , Postura/fisiología , Valores de Referencia , Soporte de Peso/fisiología , Adulto Joven
17.
BMC Complement Altern Med ; 19(1): 39, 2019 Feb 04.
Artículo en Inglés | MEDLINE | ID: mdl-30717730

RESUMEN

BACKGROUND: Alzheimer's disease (AD) and osteoporosis are progressive diseases that affect the elderly population. Both conditions are associated with fracture risk that is greater than twice that of the healthy population. Resveratrol and exercise are two treatments that have been linked with attenuation of age-related diseases, including the risk of bone fractures. In this study, we test the hypothesis that these treatments improve fracture resistance in a mouse model representative of the AD condition. METHODS: Three-month-old male 3xTg-AD mice were treated for 4 months with resveratrol or exercise or both combined, and compared with wild type mice. Exercise training was performed on a treadmill at 15 m/min for 45 min/day, 5 days/week. Resveratrol was given at 4 g/kg diet in the form of pellets. Three-point bending, cross-sectional geometric, and fluorescence analyses were conducted on tibias and compared by treatment group. RESULTS: Tibias of 3xTg mice exhibited signs of diminished bone quality and fracture under less force than age-matched wild type mice (P < 0.05). Treatment with both resveratrol and exercise improved indicators of fracture resistance and bone quality in AD mice to levels comparable to that of wild type mice (P < 0.05). CONCLUSIONS: The 3xTg mouse model of AD is at elevated risk for limb bone fracture compared to wild type controls. Treatment with resveratrol, exercise, or both in combination improves fracture resistance and cross-sectional geometric indicators of bone strength.


Asunto(s)
Enfermedad de Alzheimer/metabolismo , Prueba de Esfuerzo/efectos de los fármacos , Sustancias Protectoras/farmacología , Resveratrol/farmacología , Tibia/efectos de los fármacos , Animales , Modelos Animales de Enfermedad , Masculino , Ratones , Ratones Transgénicos , Tibia/fisiología , Fracturas de la Tibia/prevención & control , Soporte de Peso/fisiología
18.
Osteoporos Int ; 30(2): 431-439, 2019 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-30255228

RESUMEN

Potassium bicarbonate was administrated to an already alkaline diet in seven male subjects during a 21-day bed rest study and was able to decrease bed rest induced increased calcium excretion but failed to prevent bed rest-induced bone resorption. INTRODUCTION: Supplementation with alkali salts appears to positively influence calcium and bone metabolism and, thus, could be a countermeasure for population groups with an increased risk for bone loss. However, the extent to which alkalization counteracts acid-induced bone resorption or whether it merely has a calcium and bone maintenance effect is still not completely understood. In the present study, we hypothesized that additional alkalization to an already alkaline diet can further counteract bed rest-induced bone loss. METHODS: Seven healthy male subjects completed two parts of a crossover designed 21-day bed rest study: bed rest only (control) and bed rest supplemented with 90 mmol potassium bicarbonate (KHCO3) daily. RESULTS: KHCO3supplementation during bed rest resulted in a more alkaline status compared to the control intervention, demonstrated by the increase in pH and buffer capacity level (pH p = 0.023, HCO3p = 0.02, ABE p = 0.03). Urinary calcium excretion was decreased during KHCO3 supplementation (control 6.05 ± 2.74 mmol/24 h; KHCO3 4.87 ± 2.21 mmol/24 h, p = 0.03); whereas, bone formation was not affected by additional alkalization (bAP p = 0.58; PINP p = 0.60). Bone resorption marker UCTX tended to be lower during alkaline supplementation (UCTX p = 0.16). CONCLUSIONS: The more alkaline acid-base status, achieved by KHCO3 supplementation, reduced renal calcium excretion during bed rest, but was not able to prevent immobilization-induced bone resorption. However, advantages of alkaline salts on bone metabolism may occur under acidic metabolic conditions or with respect to the positive effect of reduced calcium excretion within a longer time frame. TRIAL REGISTRATION: Trial number: NCT01509456.


Asunto(s)
Reposo en Cama/efectos adversos , Bicarbonatos/uso terapéutico , Resorción Ósea/prevención & control , Suplementos Dietéticos , Compuestos de Potasio/uso terapéutico , Adulto , Bicarbonatos/farmacología , Biomarcadores/metabolismo , Resorción Ósea/etiología , Resorción Ósea/metabolismo , Calcio/orina , Estudios Cruzados , Humanos , Concentración de Iones de Hidrógeno/efectos de los fármacos , Inmovilización/efectos adversos , Inmovilización/fisiología , Masculino , Osteogénesis/efectos de los fármacos , Compuestos de Potasio/farmacología , Soporte de Peso/fisiología , Adulto Joven
19.
J Manipulative Physiol Ther ; 41(8): 672-679, 2018 10.
Artículo en Inglés | MEDLINE | ID: mdl-30573198

RESUMEN

OBJECTIVE: The purpose of this study was to evaluate the correlation among the navicular drop test, the arch angle, the Staheli index and the Chippaux-Smirak index. The reliability and the correlation among the footprint parameters were also estimated. METHODS: A cross-sectional study (n = 86; 59.3% women; 27.8 years, standard deviation: 4.8 years) was carried out. The navicular drop test was evaluated and footprint parameters using a plantar pressure platform were recorded in the dominant foot. Pearson correlation coefficients, intraclass correlation coefficient, standard error of measurement, and minimum detectable change were calculated. RESULTS: Both intrarater and interrater reliability were excellent for all the parameters evaluated (intraclass correlation coefficients > 0.880). Statistically significant correlations existed between the navicular drop test and footprints parameters (arch angle = 0,643; Staheli index = 0.633; Chippaux-Smirak index = 0.614). The footprint parameters had excellent correlation with each other (0.838-0.881). The navicular drop test and the footprint parameters studied were reproducible and thus had excellent reliability. CONCLUSION: The correlations obtained between the navicular drop test and the footprint parameters evaluated were good. The navicular drop test appears to be a reproducible, valid, and simple test for evaluating medial longitudinal arch height, having fewer disadvantages than using footprint parameters.


Asunto(s)
Antropometría/métodos , Pie/fisiología , Soporte de Peso/fisiología , Adulto , Estudios Transversales , Femenino , Humanos , Masculino , Reproducibilidad de los Resultados , Astrágalo/fisiología , Huesos Tarsianos/fisiología , Articulaciones Tarsianas/fisiología , Adulto Joven
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